Mesenchymal stem cells in the treatment of traumatic articular cartilage defects - San Francisco Stem Cell Treatment Center

Mesenchymal stem cells in the treatment of traumatic articular cartilage defects

Mesenchymal stem cells in the treatment of traumatic articular cartilage defects

A Comprehensive Review

Articular cartilage has a limited capacity to repair following injury. Early intervention is required to prevent progression of focal traumatic chondral and osteochondral defects to advanced cartilage degeneration and osteoarthritis. Novel cell-based tissue engineering techniques have been proposed with the goal of resurfacing defects with bioengineered tissue that recapitulates the properties of hyaline cartilage and integrates into native tissue. Transplantation of mesenchymal stem cells (MSCs) is a promising strategy given the high proliferative capacity of MSCs and their potential to differentiate into cartilage-producing cells – chondrocytes.

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